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VEGF120 Molecule  


VEGF120 Molecule Synonym Name

RP1-261G23.1,MGC70609,MVCD1,VEGFA,VPF

VEGF120 Protein Products

Cat No Species Product Description
VE0-M4211 Mouse ActiveMax® Recombinant Mouse VEGF120

VEGF120 Molecule Background

Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.

Reference

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