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Browse By Molecule Name --->BAFFR /TNFRSF13C Molecule

BAFFR /TNFRSF13C Molecule  


BAFFR /TNFRSF13C Molecule Synonym Name

BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin

BAFFR /TNFRSF13C Protein Products

Cat No Species Product Description
BAR-M82F0 Mouse Biotinylated Mouse BAFFR /TNFRSF13C Protein, Fc Tag, Avi Tag (Avitag™)
BAR-M5259 Mouse Mouse BAFFR / TNFRSF13C Protein, Fc Tag

BAFFR /TNFRSF13C Molecule Background

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

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