ANGPTL7 Molecule Synonym Name
ANGPTL7 Protein Products
|Cat No||Species||Product Description|
|AN7-H52H5||Human||Human ANGPTL7 / CDT6 Protein|
ANGPTL7 Molecule Background
Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
- (1) Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788.
- (2) Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693.
- (3) Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.