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CD4 Molecule  

CD4 Molecule Synonym Name


CD4 Protein Products

Cat No Species Product Description
CD4-C5256Rhesus macaqueRhesus macaque CD4 Protein, Fc Tag
CD4-C52H7Rhesus macaqueRhesus macaque CD4 Protein
CD4-H5259HumanHuman CD4 Protein, Fc Tag
LE3-H5228HumanHuman CD4 Protein

CD4 Molecule Background

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.


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