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Browse By Molecule Name --->CD4 Molecule

CD4 Molecule  


CD4 Molecule Synonym Name

CD4,CD4mut,LEU3

CD4 Protein Products

Cat No Species Product Description
CD4-C5256 Rhesus macaque Rhesus macaque CD4 Protein, Fc Tag
CD4-C52H7 Rhesus macaque Rhesus macaque CD4 Protein
CD4-H5259 Human Human CD4 Protein, Fc Tag
LE3-H5228 Human Human CD4 Protein
CD4-H82F3 Human Biotinylated Human CD4, Fc Tag & Avi Tag (Avitag™)

CD4 Molecule Background

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Reference

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