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Browse By Molecule Name --->IL13RA1 / CD213A1 Molecule

IL13RA1 / CD213A1 Molecule  


IL-13 R alpha 1 Molecule Synonym Name

IL13RA1,CD213A1,IL-13Ra,NR4,RP13-128O4.2,IL13Rα1

IL-13 R alpha 1 Protein Products

Cat No Species Product Description
IL1-H5224HumanHuman IL-13 R alpha 1 Protein
IL1-H9224HumanC13 and N15-labeled, Human IL-13 R alpha 1 Protein
IL1-M5258MouseMouse IL-13 R alpha 1 Protein, Fc Tag
IL1-M52H7MouseMouse IL-13 R alpha 1 Protein

IL-13 R alpha 1 Molecule Background

Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Reference

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