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Browse By Molecule Name --->Decorin / DSPG2 Molecule

Decorin / DSPG2 Molecule  


Decorin Molecule Synonym Name

Decorin,DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B

Decorin Protein Products

Cat No Species Product Description
DE1-H5223HumanHuman Decorin Protein

Decorin Molecule Background

Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).

Reference

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