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PDL1 / CD274 / B7-H1 Molecule  


PD-L1 / B7-H1 Molecule Synonym Name

PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1

PD-L1 / B7-H1 Protein Products

Cat No Species Product Description
PD1-C5253CynomolgusCynomolgus PD-L1 / B7-H1 Protein, Fc Tag
PD1-C52H4CynomolgusCynomolgus PD-L1 / B7-H1 Protein
PD1-H5229HumanHuman PD-L1 / B7-H1 Protein (HPLC-verified)
PD1-H5258HumanHuman PD-L1 / B7-H1 Protein, Fc Tag, low endotoxin
PD1-H5282HumanHuman PD-L1 / B7-H1 Protein, Strep Tag
PD1-H52A3HumanHuman PD-L1 / B7-H1 Protein, mouse IgG1 Fc Tag, low endotoxin (HPLC-verified)
PD1-H82E5HumanBiotinylated Human PD-L1 / B7-H1 (recommended for biopanning), Avi Tag (Avitag?)
PD1-H82F3HumanBiotinylated Human PD-L1 / B7-H1, His Tag & Fc Tag, Avi Tag (Avitag?)
PD1-H9229HumanC13 and N15-labeled, Human PD-L1 / B7-H1 Protein
PD1-M5220MouseMouse PD-L1 / B7-H1 Protein
PD1-M5251MouseMouse PD-L1 / B7-H1 Protein, Fc Tag
PD1-M52A2MouseMouse PD-L1 / B7-H1 Protein, mouse IgG2a Fc Tag, low endotoxin
PD1-M82F5MouseBiotinylated Mouse PD-L1 / B7-H1, Fc Tag, Avi Tag (Avitag?)

PD-L1 / B7-H1 Antibody Products

Cat No Species Product Description
PDL-BNA002HumanBiotinylated Anti-PD-L1 Neutralizing Antibody
PDL-NA002HumanAnti-PD-L1 Neutralizing Antibody

PD-L1 / B7-H1 Molecule Background

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

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