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Browse By Molecule Name --->PDL1 / CD274 / B7-H1 Molecule

PDL1 / CD274 / B7-H1 Molecule  


PD-L1 / B7-H1 Molecule Synonym Name

PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1

PD-L1 / B7-H1 Protein Products

Cat No Species Product Description
PD1-C5253 Cynomolgus Cynomolgus PD-L1 / B7-H1 Protein, Fc Tag
PD1-C52H4 Cynomolgus Cynomolgus PD-L1 / B7-H1 Protein
PD1-H5229 Human Human PD-L1 / B7-H1 Protein (HPLC-verified)
PD1-H5258 Human Human PD-L1 / B7-H1 Protein, Fc Tag, low endotoxin
PD1-H5282 Human Human PD-L1 / B7-H1 Protein, Strep Tag
PD1-H52A3 Human Human PD-L1 / B7-H1 Protein, mouse IgG1 Fc Tag, low endotoxin (HPLC-verified)
PD1-H82E5 Human Biotinylated Human PD-L1 / B7-H1 (recommended for biopanning), Avi Tag (AvitagTM)
PD1-H82F3 Human Biotinylated Human PD-L1 / B7-H1, His Tag & Fc Tag, Avi Tag (AvitagTM)
PD1-H9229 Human C13 and N15-labeled, Human PD-L1 / B7-H1 Protein
PD1-M5220 Mouse Mouse PD-L1 / B7-H1 Protein
PD1-M5251 Mouse Mouse PD-L1 / B7-H1 Protein, Fc Tag
PD1-M52A2 Mouse Mouse PD-L1 / B7-H1 Protein, mouse IgG2a Fc Tag, low endotoxin
PD1-M82F5 Mouse Biotinylated Mouse PD-L1 / B7-H1, Fc Tag, Avi Tag (AvitagTM)
PDL-H82F2 Human Biotinylated Human PD-L1 / B7-H1 Protein, Fc Tag, Avi Tag (Avitag™)

PD-L1 / B7-H1 Antibody Products

Cat No Species Product Description
PDL-BNA002 Human Biotinylated Anti-PD-L1 Neutralizing Antibody
PDL-NA002 Human Anti-PD-L1 Neutralizing Antibody

PD-L1 / B7-H1 Molecule Background

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

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