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Browse By Molecule Name --->CD204 / MSR1 / SCARA1 Molecule

CD204 / MSR1 / SCARA1 Molecule  


MSR1 / CD204 Molecule Synonym Name

MSR1,CD204,SCARA1,SR-A,phSR1,phSR2

MSR1 / CD204 Protein Products

Cat No Species Product Description
MS1-H5226HumanHuman MSR1 / CD204 Protein

MSR1 / CD204 Molecule Background

Macrophage scavenger receptor 1 (MSR1) is also known as CD204, SCARA1, SR-A, and is class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. Defects in MSR1 may be a cause of prostate cancer (PC) or Barrett esophagus (BE).

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