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PGF / PlGF2 / PLGF Molecule  


PLGF / PGF Molecule Synonym Name

PGF,PLGF,PlGF2,PlGF,PGFL,SHGC-10760

PLGF / PGF Protein Products

Cat No Species Product Description
PGF-H5229HumanHuman PLGF / PGF Protein

PLGF / PGF Molecule Background

Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

Reference

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