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CD30 / TNFRSF8 Molecule  


CD30 / TNFRSF8 Molecule Synonym Name

TNFRSF8,CD30,D1S166E,Ki-1

CD30 / TNFRSF8 Protein Products

Cat No Species Product Description
CD0-H5229 Human Human CD30 / TNFRSF8 Protein
CD0-H5250 Human Human CD30 / TNFRSF8 Protein, Fc Tag
CD0-H82E6 Human Biotinylated Human CD30 / TNFRSF8 Protein, Avi Tag (Avitag™)

CD30 / TNFRSF8 Molecule Background

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

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