CD30 / TNFRSF8 Molecule
CD30 / TNFRSF8 Molecule Synonym Name
CD30 / TNFRSF8 Protein Products
|Cat No||Species||Product Description|
|CD0-H5229||Human||Human CD30 / TNFRSF8 Protein|
|CD0-H5250||Human||Human CD30 / TNFRSF8 Protein, Fc Tag|
|CD0-H82E6||Human||Biotinylated Human CD30 / TNFRSF8 Protein, Avi Tag (Avitag™)|
CD30 / TNFRSF8 Molecule Background
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
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