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Browse By Molecule Name --->CA9 / CAIX Molecule

CA9 / CAIX Molecule  


CA9 Molecule Synonym Name

CAIX,CA9,CA-IX,G250,MN,P54/58N,pMW1

CA9 Protein Products

Cat No Species Product Description
CA9-H5220HumanHuman Carbonic Anhydrase IX / CA9 (138-414) Protein
CA9-H5226HumanHuman Carbonic Anhydrase IX / CA9 (38-414) Protein

CA9 Molecule Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (α, β, γ, δ and ε). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.

Reference

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