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CD200 / OX-2 Molecule  


CD200 / OX-2 Molecule Synonym Name

CD200,MOX1,MOX2,MRC,OX-2,My033

CD200 / OX-2 Protein Products

Cat No Species Product Description
OX2-H5228HumanHuman CD200 / OX-2 Protein
OX2-H5251HumanHuman CD200 / OX-2 Protein, Fc Tag

CD200 / OX-2 Molecule Background

CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

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