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Browse By Molecule Name --->EPHA7 / EHK3 Molecule

EPHA7 / EHK3 Molecule  


EphA7 Molecule Synonym Name

EPHA7,EHK3,HEK11,hEK11

EphA7 Protein Products

Cat No Species Product Description
EP7-H5221HumanHuman EphA7 Protein

EphA7 Molecule Background

Ephrin type-A receptor 7 (EPHA7) is also known as EPH homology kinase 3 (EHK3), EPH-like kinase 11 (HEK11), which belongs to the protein kinase superfamily or tyr protein kinase family or ephrin receptor subfamily. EPHA7 / EHK3 contains 1 Eph LBD (Eph ligand-binding) domain, 2 fibronectin type-III domains, 1 protein kinase domain, 1 SAM (sterile alpha motif) domain. EHK-3 / EPHA7 is widely expressed. The catalytic activity of EPHA7 / EHK3 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Reference

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