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CD68 Molecule  


CD68 / SR-D1 Molecule Synonym Name

CD68,Macrosialin,Gp110,SCARD1

CD68 / SR-D1 Protein Products

Cat No Species Product Description
MAN-H5258HumanHuman CD68 / SR-D1 Protein, Fc Tag

CD68 / SR-D1 Molecule Background

CD antigen CD68 is also known as Macrosialin, Gp110, which belongs to the LAMP family. CD68 / Macrosialin is highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 / Macrosialin could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 / Macrosialin binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

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