CD69 / CLEC2C Molecule
CD69 / CLEC2C Molecule Synonym Name
CD69 / CLEC2C Protein Products
|Cat No||Species||Product Description|
|CD9-H5222||Human||Human CD69 / CLEC2C Protein|
CD69 / CLEC2C Molecule Background
Early activation antigen CD69 is also known as C-type lectin domain family 2 member C (CLEC2C), Activation inducer molecule (AIM), Early T-cell activation antigen p60, Leukocyte surface antigen Leu-23. CD69 contains one C-type lectin domain. CD69 / CLEC2C is expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. CD69 is induced by antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes and by interaction of IL-2 with the p75 IL-2R on the surface of NK cells. CD69 / CLEC2C involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
- (1) (1) Natarajan K., et al., 2000, Biochemistry 39:14779-14786.
- (2) (2) Llera A.S., et al., 2001, J. Biol. Chem. 276:7312-7319.
- (3) (3) Vanek O., et al., 2008, FEBS J. 275:5589-5606.