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Your Position: Home > NTRK2 / TRKB Molecule

TrkB / NTRK2 Molecule Synonym Name

NTRK2,TRKB,GP145-TrkB

TrkB / NTRK2 Protein Products

Cat No Species Product Description
NT2-H5228HumanHuman TrkB / NTRK2 Protein
NT2-H5254HumanHuman TrkB / NTRK2 Protein, Fc Tag

TrkB / NTRK2 Molecule Background

Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.

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