CD27 / TNFRSF7 Molecule
CD27 / TNFRSF7 Molecule Synonym Name
CD27 / TNFRSF7 Protein Products
|Cat No||Species||Product Description|
|CD7-H5254||Human||Human CD27 / TNFRSF7 Protein, Fc Tag|
|TN7-H82F6||Human||Biotinylated Human CD27 / TNFRSF7 Protein, Fc Tag, Avi Tag (Avitag?)|
CD27 / TNFRSF7 Molecule Background
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
- (1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
- (2) Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216.
- (3) Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.