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CD58 / LFA3 Molecule  


CD58 / LFA-3 Molecule Synonym Name

CD58,LFA3,Ag3

CD58 / LFA-3 Protein Products

Cat No Species Product Description
LF3-H5225HumanHuman CD58 / LFA-3 Protein
LF3-H5256HumanHuman CD58 / LFA-3 Protein, Fc Tag

CD58 / LFA-3 Molecule Background

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

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