FABP2 / FABPI Molecule
FABP2 / I-FABP Molecule Synonym Name
FABP2 / I-FABP Protein Products
|Cat No||Species||Product Description|
|FA2-H5149||Human||Human FABP2 / I-FABP Protein|
FABP2 / I-FABP Molecule Background
Fatty acid-binding protein 2 (FABP2), is also known as Fatty acid-binding protein, intestinal (FABPI), Intestinal-type fatty acid-binding protein (I-FABP). FABP2 belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. FABP2 / FABPI is expressed in the small intestine and at much lower levels in the large intestine and is highest expressed in the jejunum. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
- (1) Pelsers M.M.A.L., et al., 2003, Clin. Biochem. 36:529-535.
- (2) Darimont C., et al., 1999, Am. J. Physiol. 276:G606-G612.