ICAM2 / CD102 Molecule
ICAM-2 / CD102 Molecule Synonym Name
ICAM-2 / CD102 Protein Products
|Cat No||Species||Product Description|
|IC2-H5220||Human||Human ICAM-2 / CD102 Protein|
ICAM-2 / CD102 Molecule Background
Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
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- (3) Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.