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KLK11 Molecule  


Kallikrein 11 Molecule Synonym Name

KLK11,Kallikrein-11,Hippostasin,hK11,PRSS20,TLSP

Kallikrein 11 Protein Products

Cat No Species Product Description
KL1-H5224HumanHuman Kallikrein 11 / KLK-11 Protein

Kallikrein 11 Molecule Background

Kallikrein 11 (KLK11) is also known as Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP, which belongs to the peptidase S1 family and Kallikrein subfamily. KLK11 contains one peptidase S1 domain. KLK11 is expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level). Kallikrein 11 /KLK11 is a possible multifunctional protease and efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. KLK11 cleaves synthetic peptides after arginine but not lysine residues.

Reference

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