Ephrin-B1 Molecule Synonym Name
Ephrin-B1 Protein Products
|Cat No||Species||Product Description|
|EF1-H5223||Human||Human Ephrin-B1 / EFNB1 Protein|
Ephrin-B1 Molecule Background
Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.
- (1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
- (2) Brueckner K., et al., 1999, Neuron 22:511-524.