Kallikrein 3 Molecule Synonym Name
Kallikrein 3 Protein Products
|Cat No||Species||Product Description|
|KL3-H5226||Human||Human Kallikrein 3 / KLK-3 Protein|
Kallikrein 3 Molecule Background
Kallikrein-3 (KLK3) is also known as Prostate-specific antigen (PSA), APS, Gamma-seminoprotein (Seminin), P-30 antigen, Semenogelase, is a glycoprotein enzyme, is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. The preferential cleavage site of KLK3 is “-Tyr-|-Xaa-“, the catalytic activity is inhibited by SERPINA5 and is strongly inhibited by Zn2+. KLK3 hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
- (1) Espana F., et al., 1991, Thromb. Res. 64:309-320.
- (2) Menez R., et al., 2008, J. Mol. Biol. 376:1021-1033.