PTH1R / PTHR1 Molecule
PTH1R / PTHR1 Molecule Synonym Name
PTH1R / PTHR1 Protein Products
|Cat No||Species||Product Description|
|PTR-H5222||Human||Human PTH1R / PTHR1 Protein|
PTH1R / PTHR1 Molecule Background
Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
- (1) Johnston C.A., et al., 2008, Structure 16:1086-1094.
- (2) Pioszak A.A., et al., 2010, J. Biol. Chem. 285:12435-12444.