CNDP1 / CPGL2 Molecule
CNDP1 Molecule Synonym Name
CNDP1 Protein Products
|Cat No||Species||Product Description|
|CN1-H5224||Human||Human CNDP1 Protein|
CNDP1 Molecule Background
Beta-Ala-His dipeptidase is also known as Carnosine dipeptidase 1 (CNDP1), CNDP dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CPGL2, which belongs to the peptidase M20A family. CNDP1 is found in serum and adult nervous central system. CNDP1 preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. The catalytic activity of CNDP1 is inhibited by the metal chelator 1,10-o-phenantrolin and the inhibitory concentration 50% (IC50) is 5 ?M.
- (1) Lenney J.F., et al., 1982, Clin. Chim. Acta 123:221-231.
- (2) Lenney J.F., et al., 1983, Clin. Chim. Acta 132:157-165.
- (3) Teufel M., et al., 2003, J. Biol. Chem. 278:6521-6531.