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SLAMF7 / CD319 Molecule  

SLAMF7 / CD319 Molecule Synonym Name


SLAMF7 / CD319 Protein Products

Cat No Species Product Description
SL7-H5225HumanHuman SLAMF7 / CRACC / CD319 Protein
SL7-H5256HumanHuman SLAMF7 / CRACC / CD319 Protein, Fc Tag

SLAMF7 / CD319 Molecule Background

SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.