Cystatin S / CST4 Molecule Synonym Name
Cystatin S / CST4 Protein Products
|Cat No||Species||Product Description|
|CS4-H5223||Human||Human Cystatin S / CST4 Protein|
Cystatin S / CST4 Molecule Background
Cystatin-4 (CST4) is also known as Cystatin-S, Salivary acidic protein 1, which is a secreted protein, which belongs to the cystatin family. Cystatin-S is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in saliva, tears, urine and seminal fluid. Cystatin-4 / Cystatin S strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
- (1) Lamkin M.S., et al., 1991, Arch. Biochem. Biophys. 288:664-670.
- (2) Ryan C.M., et al., 2010, J. Am. Soc. Mass Spectrom. 21:908-917.
- (3) Isemura S., et al., 1991, J. Biochem. 110:648-654.