CD300A / CLM-8 Molecule
CD300a / LMIR1 Molecule Synonym Name
CD300a / LMIR1 Protein Products
|Cat No||Species||Product Description|
|CDA-H5257||Human||Human CD300a / LMIR1 Protein, Fc Tag|
CD300a / LMIR1 Molecule Background
CD300 antigen-like family member A (CD300A) is also known as CMRF35-like molecule 8 (CLM-8), CMRF-35-H9, CMRF35-H, Immunoglobulin superfamily member 12 (IGSF12), NK inhibitory receptor, LMIR1, which belongs to the CD300 family. CD300A contains one Ig-like V-type (immunoglobulin-like) domain. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is a inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
- (1) Green B.J., et al., 1998, Int. Immunol. 10:891-899.
- (2) Clark G.J., et al., 2000, Tissue Antigens 55:101-109.
- (3) Bachelet I., et al., 2005, J. Immunol. 175:7989-7995.