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TNFRSF17 Molecule  


BCMA / TNFRSF17 Molecule Synonym Name

TNFRSF17,CD269,BCM,BCMA

BCMA / TNFRSF17 Protein Products

Cat No Species Product Description
BC7-H5254 Human Human BCMA / TNFRSF17 Protein, Fc Tag
BC7-H82F0 Human Biotinylated Human BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
BCA-C82F4 Cynomolgus Biotinylated Cynomolgus BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
BCA-H522y Human Human BCMA / TNFRSF17 Protein
BCA-HF254 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag

BCMA / TNFRSF17 Molecule Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Reference

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