CNTF R alpha Molecule Synonym Name
CNTFR,CNTF R alpha
CNTF R alpha Protein Products
|Cat No||Species||Product Description|
|CNR-H5225||Human||Human CNTF R alpha Protein|
CNTF R alpha Molecule Background
Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.
- (1) Davis S., et al., 1991, Science 253 (5015): 59–63.
- (2) Sleeman MW., et al., 2000, Pharm Acta Helv 74 (2–3): 265–72.