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TACSTD2 Molecule  


TROP-2 Molecule Synonym Name

TACSTD2,GA733-1,M1S1,TROP2

TROP-2 Protein Products

Cat No Species Product Description
TR2-H5221HumanHuman TROP-2 / TACSTD2 Protein

TROP-2 Molecule Background

Tumor-associated calcium signal transducer 2 (TACSTD2) is also known as Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1 (M1S1), Pancreatic carcinoma marker protein GA733-1, which belongs to the EPCAM family. TACSTD2 contains one thyroglobulin type-1 domain. TACSTD2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. TACSTD2 transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of TACSTD2 result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

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