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PLAUR / CD87 Molecule  


uPAR / PLAUR Molecule Synonym Name

uPAR,PLAUR,CD87,MO3

uPAR / PLAUR Protein Products

Cat No Species Product Description
UPR-H5226HumanHuman uPAR / PLAUR Protein

uPAR / PLAUR Molecule Background

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Reference

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