Cathepsin D Molecule Synonym Name
Cathepsin D Protein Products
|Cat No||Species||Product Description|
|CTD-H5226||Human||Human Cathepsin D / CTSD Protein|
Cathepsin D Molecule Background
Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extrcellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
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- (3) Papassotiropoulos A., et al., 2000, Ann. Neurol. 47:399-403.