HSP90AA1 Molecule Synonym Name
HSP90AA1 Protein Products
|Cat No||Species||Product Description|
|HS1-H511y||Human||Human HSP90AA1 / HSP86 Protein, Tag Free|
|HS1-H513x||Human||Human HSP90AA1 / HSP86 Protein, GST Tag|
HSP90AA1 Molecule Background
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
- (1) Martinez-Ruiz A., et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102:8525-8530.
- (2) Forsythe H.L., et al., 2001, J. Biol. Chem. 276:15571-15574.
- (3) Yang J., et al., 2005, EMBO J. 24:1-10.