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TYRO3 / DTK Molecule  


TYRO3 / Dtk Molecule Synonym Name

TYRO3,BYK,DTK,RSE,SKY,TIF

TYRO3 / Dtk Protein Products

Cat No Species Product Description
TY3-H5251HumanHuman TYRO3 / Dtk Protein, Fc Tag

TYRO3 / Dtk Molecule Background

Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

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