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TREM1 / CD354 Molecule  


TREM1 / CD354 Molecule Synonym Name

TREM1, CD354

TREM1 / CD354 Protein Products

Cat No Species Product Description
TR1-H5220HumanHuman TREM1 /CD354 Protein
TR1-H5251HumanHuman TREM1 /CD354 Protein,With C-Fc Tag

TREM1 / CD354 Molecule Background

Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.

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