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GITR / CD357 Molecule  

GITR Molecule Synonym Name


GITR Protein Products

Cat No Species Product Description
GIR-C5255Rhesus macaqueRhesus macaque GITR / TNFRSF18 Protein, Fc Tag
GIR-H5228HumanHuman GITR / TNFRSF18 Protein
GIR-M5220MouseMouse GITR / TNFRSF18 Protein
GIR-M5251MouseMouse GITR / TNFRSF18 Protein, Fc Tag
GIR-R5222RatRat GITR / TNFRSF18 Protein
GIR-R5253RatRat GITR / TNFRSF18 Protein, Fc Tag

GITR Molecule Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.


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