GITR / CD357 Molecule
GITR Molecule Synonym Name
GITR Protein Products
|Cat No||Species||Product Description|
|GIR-C5255||Rhesus macaque||Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag|
|GIR-H5228||Human||Human GITR / TNFRSF18 Protein|
|GIR-M5220||Mouse||Mouse GITR / TNFRSF18 Protein|
|GIR-M5251||Mouse||Mouse GITR / TNFRSF18 Protein, Fc Tag|
|GIR-R5222||Rat||Rat GITR / TNFRSF18 Protein|
|GIR-R5253||Rat||Rat GITR / TNFRSF18 Protein, Fc Tag|
GITR Molecule Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
- (1) Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
- (2) Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.