ARG1 Molecule Synonym Name
ARG1 Protein Products
|Cat No||Species||Product Description|
|AR1-H5228||Human||Human Arginase 1 / ARG1 Protein|
ARG1 Molecule Background
Arginase-1 (ARG1) is also known as Liver-type arginase, Type I arginase, which belongs to the arginase family. Arginase-1 / ARG1 is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. Defects in Arginase-1 / ARG1 are the cause of argininemia (ARGIN).
- (1) Ikemoto M., et al., 1990, Biochem. J. 270:697-703.
- (2) Di Costanzo L., et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102:13058-13063.
- (3) Di Costanzo L., et al., 2007, J. Am. Chem. Soc. 129:6388-6389.