PLA2G1B / PLA2 Molecule
PLA2G1B Molecule Synonym Name
PLA2G1B Protein Products
|Cat No||Species||Product Description|
|PLB-H5228||Human||Human PLA2G1B Protein|
PLA2G1B Molecule Background
Phosphatidylcholine 2-acylhydrolase 1B (PLA2G1B) is also known as Phospholipase A2 (PLA2), PLA2A, PPLA2, which belongs to the phospholipase A2 family. PLA2G1B is activated by trypsin cleavage in the duodenum and can also be activated by thrombin or autocatalytically. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules.
- (1) Grataroli R., et al., 1982, Eur. J. Biochem. 122:111-117.
- (2) Xu W., et al., 2009, J. Biol. Chem. 284:16659-16666.