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KNG1 Molecule  


Kininogen 1 Molecule Synonym Name

KNG1,Kininogen-1,HMWK,BDK,KNG

Kininogen 1 Protein Products

Cat No Species Product Description
KN1-H5225HumanHuman Kininogen 1 / KNG1 (LMW) Protein

Kininogen 1 Molecule Background

Kininogen-1 (KNG1) is also known as HMWK, BDK, KNG, is a secreted protein which contains three cystatin domains. KNG1 can be cleaved into the following six chains: Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

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