GLRX / GRX Molecule
GLRX1 Molecule Synonym Name
GLRX1 Protein Products
|Cat No||Species||Product Description|
|GLX-H5149||Human||Human Glutaredoxin 1 / GLRX1 Protein|
GLRX1 Molecule Background
Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.
- (1) Papov V.V., et al., 1994, Protein Sci. 3:428-434.
- (2) Yang Y., et al., 1998, Biochemistry 37:17145-17156.