IFN-alpha / beta R1 Molecule Synonym Name
IFN-alpha / beta R1 Protein Products
|Cat No||Species||Product Description|
|IF1-H5253||Human||Human IFN-alpha / beta R1 Protein, Fc Tag|
IFN-alpha / beta R1 Molecule Background
Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
- (1) Colamonici O., et al., 1994, Mol. Cell. Biol. 14:8133-8142.
- (2) Li X., et al., 1997, Mol. Cell. Biol. 17:2048-2056.
- (3) Russell-Harde D., et al., 1999, Biochem. Biophys. Res. Commun. 255:539-544.