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IL5RA / CD125 Molecule  


IL-5 R alpha / CD125 Molecule Synonym Name

IL5Ra,CD125

IL-5 R alpha / CD125 Protein Products

Cat No Species Product Description
ILA-H52H4HumanHuman IL-5 R alpha / CD125 Protein

IL-5 R alpha / CD125 Molecule Background

Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.

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