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Browse By Molecule Name --->IL12 / P70 Molecule

IL12 / P70 Molecule  


IL-12 Molecule Synonym Name

IL12,p70,Interleukin-12

IL-12 Protein Products

Cat No Species Product Description
IL2-H4210 Human ActiveMax® Recombinant Human IL-12

IL-12 Molecule Background

Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-γ and TNF-α from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-γ. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.

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