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LTBR / TNFRSF3 Molecule  


LTBR / TNFRSF3 Molecule Synonym Name

LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII

LTBR / TNFRSF3 Protein Products

Cat No Species Product Description
LTR-H5251HumanHuman LTBR / TNFRSF3 Protein, Fc Tag

LTBR / TNFRSF3 Molecule Background

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

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