S100A14 / S114 Molecule
S100A14 Molecule Synonym Name
S100A14 Protein Products
|Cat No||Species||Product Description|
|S14-H5121||Human||Human S100A14 Protein|
S100A14 Molecule Background
Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
- (1) Jin Q., et al., 2011, PLoS ONE 6:E19375-E19375.
- (2) Chen H., et al., 2012, J. Biol. Chem. 287:17109-17119.
- (3) Sapkota D., et al., 2012, Oral Oncol. 48:219-225.