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FETUB Molecule  


Fetuin B / FETUB Molecule Synonym Name

FETUB,Fetuin-B,16G2,Gugu

Fetuin B / FETUB Protein Products

Cat No Species Product Description
FEB-H52H7HumanHuman Fetuin B / FETUA Protein

Fetuin B / FETUB Molecule Background

Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.

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