GPD1 / GPD-C Molecule
GPD1 / GPD-C Molecule Synonym Name
GPD1 / GPD-C Protein Products
|Cat No||Species||Product Description|
|GP1-H5148||Human||Human GPD1 / GPD-C Protein|
GPD1 / GPD-C Molecule Background
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD1), a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, is also known as GPD-C or GPDH-C. The function of GPD1 is inhibited by zinc ions and sulfate. GPD1 can also interact selectively and non-covalently with nicotinamide adenine dinucleotide (NAD), a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. Mutations in GPD1 gene are a cause of Hypertriglyceridemia, transient infantile (HTGIT).
- (1) Basel-Vanagaite L., et al., 2012, Am. J. Hum. Genet. 90:49-60.
- (2) Ou X., et al., 2006, J. Mol. Biol. 357:858-869.