Recombinant Human THSD1 /TMTSP Protein (rh THSD1 / TMTSP) Glu 25 - Ile 361 (Accession # AAH63842) was produced in human 293 cells (HEK293) at ACROBiosystems.
rh THSD1 / TMTSP is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 39.7 kDa. The predicted N-terminus is Glu 25. DTT-reduced Protein migrates as 60-75 kDa in SDS-PAGE due to glycosylation.
Less than 1.0 EU per μg of the rh THSD1 / TMTSP by the LAL method.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Contact us for customized product form or formulation.
See Certificate of Analysis for reconstitution instructions and specific concentrations.
Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Thrombospondin type-1 domain-containing protein 1 (THSD1) is also known as Transmembrane molecule with thrombospondin module (TMTSP), which is a single-pass type I membrane protein and contains a type 1 thrombospondin domain that is found in thrombospondin, a number of proteins involved in the complement pathway, as well as extracellular matrix proteins. In addition, THSD1 is widely expressed on endothelial cells, with highest expression in the lung. THSD1's ligand and function are unknown, but it is postulated that THSD1 may be involved in the regulation of vasculogenesis and/or angiogenesis through its interaction with its specific ligand.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.