Recombinant Human LXN /Latexin Protein (rh LXN / Latexin) Glu 2 - Glu 222 (Accession # AAH08438) was produced in E.coli cells at ACROBiosystems.
rh LXN / Latexin is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 26.6 kDa. The predicted N-terminus is Met. DTT-reduced Protein migrates as 32 kDa in SDS-PAGE .
Less than 1.0 EU per μg of the rh LXN / Latexin by the LAL method.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 50 mM tris, 150 mM Nacl, pH8.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Contact us for customized product form or formulation.
See Certificate of Analysis for reconstitution instructions and specific concentrations.
Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Latexin (LXN) ,a member of the protease inhibitor I47 (latexin) family, is also known as endogenous carboxypeptidase inhibitor (ECI), tissue carboxypeptidase inhibitor (TCI) and protein MUM, which is highly expressed in heart, prostate, ovary, kidney, pancreas and colon, moderate or low in other tissues including brain. LXN is hardly reversible, non-competitive, and a potent inhibitor of CPA1, CPA2 and CPA4. LXN may play a role in inflammation as well.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.